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Topical peptides act locally in skin or mucosa

GHK-Cu is not approved by the FDA or any regulatory agency for therapeutic or cosmetic use

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Further, the ability of MeHg to inactivate GPx-1 at low nanomolar concentrations suggests that loss of GPx-1 activity may contribute to MeHg toxicity

Data availability The shotgun metagenomics dataset generated during this study (i.e., NovaSeq X Plus Series paired-end 150 fastq reads) can be found in the European Nucleotide Archive repository at: with accession number PRJEB85873.The remaining datasets used and/or analyzed during the current study are included in the manuscript or supporting files