From the side effects, to the cost, to getting one prescribed from your docthere are both physical and logistical challenges between you and the weight loss meds
GLP-1R neurons in the DMH and other hypothalamic nuclei regulate multiple aspects of eating behavior, presenting potential therapeutic targets for GLP-1R-based therapies and other drug candidates
Adding a medication like tirzepatide, which also affects insulin and glucose, can make blood sugar levels even more unpredictable, increasing the risk of hypoglycemia (low blood sugar)
He L, Zhang S, Zhang X, Liu R, Guan H, Zhang H
In liver hepatocellular carcinoma, there was a slight improvement in survival with high GLP1R expression (HR = 1.40, ogrank p = 0.097)