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Absorption across routes Route-dependent absorption: IP (intraperitoneal): rapid absorption through peritoneal surface, near-complete systemic delivery

Caveolin-1 expression is critical for vascular endothelial growth factor-induced ischemic hindlimb collateralization and nitric oxide-mediated angiogenesis

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Repeated needle punctures create micro-channels through the stopper that can allow air ingress and potential contamination

The best result was a modest 2.6 kilograms in a short trial, and that result did not hold up in the larger, longer study designed to confirm it