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Cost and Insurance Coverage Out-of-pocket costs for these weight loss medications remain high: Ozempic / Wegovy / Rybelsus: $800 $1,200 per month Mounjaro / Zepbound: $1,000 $1,300 per month While insurance coverage often includes Ozempic and Mounjaro for diabetes, Wegovy and Zepbound (indicated for weight management) may be excluded or require prior authorization