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From a system perspective, increased use of these medications may help reduce long-term healthcare costs by preventing or mitigating expensive chronic diseases

For example [49], reported elevated levels of nitric oxide (NO) and malondialdehyde (MDA), alongside decreased superoxide dismutase (SOD) activity and reduced glutathione (GSH) levels in the bronchoalveolar lavage fluids and lung tissues of Hg- exposed rats

In STEP-2 (NCT03552757), semaglutide (1.02.4 mg/week subcutaneously) reduced albuminuria by 25% versus placebo in normoalbuminuric patients with overweight/obesity but not T2DM and by 4157% in 166 participants with A2/A3 albuminuria [70]

Its wider availability in India can be a meaningful step toward improving long-term metabolic health outcomes

While GHK-Cu delivers copper in a chelated form that prevents oxidative damage, extended continuous use could theoretically affect copper homeostasis