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This effect was evidenced by alterations in total and ferrous iron levels in the hippocampus and an increase in the expression of PEBP1, ERK1/2, and key ferroptosis-related proteins, including GPX4, FTH1, ACSL4, and COX2 ( 2+ , SLC7A11, and GPX4 (Yang et al., 2024c)
Natural products have emerged as promising therapeutic agents for preventing and ameliorating renal fibrosis due to their multi-target efficacy and favorable safety profiles
Natural herbs and botanical drug products which have been widely reported in vitro showed favorable outcomes in the treatment of uterine fibroid
By "sacrificing" an electron to stabilize these molecules, glutathione prevents them from causing systemic harm