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Cardiovascular outcome trials in patients with T2D have demonstrated the efficacy of GLP-1 RAs in reducing major adverse cardiovascular events, including cardiovascular death, MI and stroke, regardless of glycaemic control

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This is due to growth hormone and IGF-1s synergistic effects

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BPC-157 treatment in fibroblast cell models demonstrates dose-dependent increases in paxillin phosphorylation at Y31 and Y118 residues, measured using quantitative immunofluorescence and flow cytometry-based approaches