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These side effects mostly show up in the digestive system

Other significant safety considerations include a history of pancreatitis, acute kidney injury risk, diabetic retinopathy complications in patients with type 2 diabetes, gallbladder disease, hypoglycemia risk in patients using other diabetes medications, and mental health monitoring for mood changes or suicidal ideation

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Men who lose significant weight often see natural testosterone rise, which may reduce or eliminate the need for supplemental testosterone