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Conversely, taxa enriched in PD, such as members of the Enterobacteriaceae family, Akkermansia, and Desulfovibrio, are associated with heightened lipopolysaccharide burden, mucin degradation, and increased generation of reactive oxygen species, collectively amplifying innate immune activation and pro-inflammatory cascades
Offen D, Ziv I, Sternin H, Melamed E, Hochman A
(2024, October 2)
10.3389/fped.2021.650624 80
As IC/BPS might be multifactorial, future research should target different implicated pathways simultaneously and study the role of reactive oxygen species as a root cause in IC/BPS
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