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We found significant decrease in DNA polymerase kappa (POLK) (log2 fold = 2.987, P = 0.026), CD109 molecule (CD109) (log2 fold = 3.977, P = 0.027), cathelicidin antimicrobial peptide (CAMP) (log2 fold = 5.020, P = 0.012), nucleolar protein interacting with the FHA domain of MKI67 (NIFK) (log2 fold = 5.048, P = 0.019) and serglycin (SRGN) (log2 fold = 6.286, P = 0.009) GP levels compared with the levels before 4-week intermittent fasting

The massive synthesis of pyruvate and the activation of the mTOR-HIF-1 pathway will further promote the aerobic glycolytic process, facilitating the TI process (134, 135)

In controlled laboratory settings, it is utilized to study the relationship between NNMT inhibition, NAD+ biosynthesis, and cellular energy metabolism

[DOI] [PubMed] [Google Scholar] 44.Pecoits-Filho R., Lindholm B., Stenvinkel P