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Other xenobiotics are neutralized and eliminated when glutathione joins them (conjugates)

Among the most frequent adverse effects are: vomiting, nausea, diarrhea, hypoglycemia in case of use with oral diabetes medications other than sulfonylureas or insulin, gastritis, stomach pain, fatigue, constipation, dizziness, retinopathy

The 6-pyruvoyltetrahydropterin synthase enzyme is encoded by the PTS gene which is located on chromosome 11q23.1 and is composed of 6 exons that encode a 145 amino acid protein