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The copper-bound tripeptide (glycyl-L-histidyl-L-lysine) has an extraordinarily high copper binding affinity with a pK of 16.44, which is approximately 10 million times higher than other tripeptides

If you have additional risk factors, such as a vegetarian or vegan diet (which may be lower in B12-containing foods), a history of gastrointestinal surgery, or certain medical conditions like pernicious anemia, your healthcare provider may recommend monitoring your B12 levels and considering supplementation, including B12 shots if necessary

Altered fecal microbiota composition in patients with major depressive disorder

Markers of oxidative stress and neuroprogression in depression disorder

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