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The presence of B12 deficiency itself may indicate an underlying digestive disorder that requires specific investigation and management

They also have the potential to address the psychological barriers which can discourage patients from seeking treatment

J Bacteriol 189:39693976 Beste DJ, Noh K, Niedenfuhr S, Mendum TA, Hawkins ND, Ward JL, Beale MH, Wiechert W, McFadden J (2013) 13C-flux spectral analysis of host-pathogen metabolism reveals a mixed diet for intracellular Mycobacterium tuberculosis

B vitamins are often prescribed together because deficiency of one B vitamin usually signals that others are deficient