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10.2337/db10-0098

cyclospora outbreaks were reported each year

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the invention concerns isolated or purified coding segments or isolated or purified gene portions and recombinant vectors incorporating DNA sequences that encode CDR regions of VEGFR2-blocking, human anti-VEGF antibody heavy and/or light chains of the invention, such as r84 heavy and/or light chains, that comprise at least a first sequence region that includes an amino acid sequence region of at least about 75%, more preferably, at least about 80%, more preferably, at least about 85%, more preferably, at least about 90% and most preferably, at least about 95% or so amino acid sequence identity to the amino acid sequence of SEQ ID NO:3 or SEQ ID NO:4

At this time, they should not replace proven treatments but may have a role in carefully selected, closely monitored patients