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The experience tends to feel less stimulating and more like a gradual change in appetite and fullness

Key clinical trial comparisons They havent been pitted against each other in large-scale, direct head-to-head trials, but cross-trial analyses and meta-analyses give us a clear signal

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Wadden told Newsweek that the exclusion of people with a history of significant mental illness from the STEP trials meant "carefully controlled examinations are needed of persons who have greater levels of depression and other psychiatric complications" before the drugs are concluded to be completely safe for those people

Shimizu T, Numata T, Okada Y