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However, it's worth noting that beta blockers are not recommended as first-line treatment for uncomplicated hypertension according to NICE guideline NG136

Effective therapy is justified in preventing serious conditions that may develop due to improper treatment or neglect of symptoms

doi: 10.1152/physiol.00003.2018 2 Echouffo-TcheuguiJBSelvinE

Lam M, Pereira AAL, Marie PK, Davis JS, Yu RX, Morris J, Manyam GC, Broom BM, Maru DM, Katkhuda R, Menter D, Kopetz S

72 Magnesium readily enters the brain following mild TBI in rodents, but has not been shown to significantly increase in the CNS when supplemented in humans