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Journal of Biological Chemistry 277 , 4944649452, doi: 10.1074/jbc.M209372200 (2002)

Recruitment of creb binding protein is sufficient for creb-mediated gene activation

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When you are losing weight rapidly and trying to preserve muscle, protein intake becomes non-negotiable

At Week 26, treatment with a 2 mg dose of EGRIFTA (1 mg/vial formulation) resulted in a reduction from baseline in mean trunk fat of 1.0 kg in Study 1 and 0.8 kg in Study 2, respectively (compared with an increase of 0.4 kg in Study 1 and of 0.2 kg in Study 2, respectively, in patients receiving placebo)