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Genetic and epigenetic factors together with visceral fat accumulation, pancreas cell dysfunction and changes in gut brain axis are responsible for the development of both diseases ( Acetylcholine is a primary excitatory neurotransmitter, which regulates gastrointestinal motility through M1-5 muscarinic receptors either directly on smooth muscles cells or indirectly through the enteric nervous system
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ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
Cvitkovi, D., Lisica, P., Zoric, Z., Repaji, M., Pedisic, S., Dragovic-Uzelac, V., & Balbino, S