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PUFAs, but not saturated or MUFAs, inhibit lipogenic genes by downregulating SREBP-1c

SLU-PP-332 is a novel synthetic pan-agonist of the estrogen-related receptors (ERR, ERR, ERR), originally developed at Saint Louis University and characterised in recent pre-clinical literature as an exercise mimetic. It is widely studied in research models exploring mitochondrial biogenesis, fatty-acid oxidation, and metabolic endurance

Extensive published preclinical research, primarily from rat and mouse models

It does not require conversion by the body, making it easier to utiliseespecially for those with impaired methylation pathways