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Neurology 1984, 34: 1128-1129

( B ) Volcano plot showing lipid alterations in mouse livers following GSH depletion

Human medical use remains uncertain because BPC-157 lacks FDA approval, standardized dosing, and strong controlled clinical evidence

In a 3-year randomized open-label study, epalrestat was well tolerated and prevented the deterioration of median motor nerve conduction velocity, minimal F-wave latency and vibration perception threshold compared with the control group with DPN [118]