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Description

Epithalon Epithalon (Epitalon) es un tetrapptido sinttico estudiado por su posible papel en la activacin de la telomerasa y la regulacin del envejecimiento celular

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Wei, Z., Li, X., Liu, Q

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Sian J, et al

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10.3727/105221621X16104581979144 45 JaeschkeH.RamachandranA.ChaoX.DingW

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Epigenetic dysregulation: Copper inhibits histone deacetylases (HDACs) and activates histone acetyltransferases (HATs), causing chromatin hyperacetylation and aberrant transcription of pro-apoptotic genes (e.g., Bax, p53 up-regulated modulator of apoptosis protein (PUMA)) [144]

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