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5.2 Role of the CTGF signaling pathway in OA synovial fibrosis The TGF- target CTGF, also known as CCN2, plays a crucial role in physiological and pathological processes such as inflammation, wound healing, tumorigenesis, and fibrosis (131)

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[32] Takele WW, Vesco KK, Josefson J, et al

6 Practical issues when prescribing GLP-1RA in T1D GLP-1RA are not currently approved for treatment of T1D, but they may still be covered by insurance if prescribed to treat obesity in these patients (although insurance coverage for obesity remains limited)

Ozempic (semaglutide for type 2 diabetes) Ozempic contains the same drug as Wegovy (semaglutide) but is licensed for type 2 diabetes and has a lower maximum dose of 2 mg