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Mechanism of action These agents cause direct relaxation of peripheral arterial smooth muscle and thereby significantly decrease peripheral resistance

Many of these substances were designated as Category 2 substances on the FDAs interim 503A Bulks List in 2023, reflecting the FDAs preliminary determination that they presented significant safety risks in the context of compounding

Potential Research Applications Metabolic Studies Investigated for its potential effects on energy balance and metabolic function

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Some benefits, like improved skin radiance and sustained energy, build over time with consistent treatments