Planning your vial purchases to align with your escalation schedule prevents the scenario where you have half a vial at a concentration you no longer need
Additionally, missingness in key clinical variablessuch as lab values and follow-up weightsmay have introduced selection bias, as patients included in the analyses may differ systematically from those without complete data
doi:10.1038/nri2925 Hlscher C
The endpoint algorithms were validated and showed a sensitivity of over 99% for mortality in the National Death Index, a positive predictive value of 94% for myocardial infarction, 95% for stroke and 98% for heart failure hospitalization 33,35,36,37,38,39,40
This reflects adaptive remodeling , not disease