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These anti-inflammatory actions are further potentiated by TCM-derived phytochemicals, which synergistically suppress NLRP3/ASC/caspase-1 complex formation, reduce IL-1 maturation, and modulate TGF-/Smad pathway phosphorylation, ultimately attenuating renal fibrotic responses (111, 112)

Its bitter taste was usually disguised with herbs and spices

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By pairing the synthetic pentadecapeptide with an L-Arginine protective buffer, the compound exhibits an exceptional oral bioavailability profile exceeding 90%