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Over-representation analysis of the DEGs was done by using ShinyGo 0.80 to show the top 20 pathways, ranked based on fold enrichment, and false discovery rate (FDR 0.05)

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Hormone Metabolic Res

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Effectiveness for lowering LDL cholesterol in adults and children with HoFH A 12-week clinical trial comparing Repatha with a placebo found that Repatha effectively lowered LDL cholesterol levels in adults and children with HoFH

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