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In human endothelial cells in culture carnitine and its acyl derivatives (at 0.5-2 mM) were shown to increase gene and protein expression of HO-1 [123]

It also targets adipose tissue (Fat) in the abdominal area

Thus, we could surmise that fasting-activated AMPK signalling in adipocytes further aggravates the already heightened p53 signalling under HFD 70

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