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Our findings from this study strengthen the evidence that increased homocysteine is associated with ASD linearly and may serve as a novel and sensitive biomarker for distinguishing children with ASD from healthy subjects

Usually, B12 is absorbed in the stomach with the help of an intrinsic factor protein

Additionally, LONP1 knockdown activates the nuclear factor erythroid 2-related factor 2 (Nrf2)/Keap1 signaling pathway and upregulates glutathione peroxidase 4 (GPX4), thereby reversing erastin-induced ferroptosis in pancreatic cancer cells [159]

6 Indirect antioxidants While some molecules act like antioxidants by directly scavenging free radicals, there are some bioactive compounds that can support oxidative stress balance indirectly, by regulating inflammatory pathways, redox signaling or mitochondrial function

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