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Since the synthesis of the first therapeutic peptide, insulin, in 1921, remarkable achievements have been made resulting in the approval of more than 80 peptide drugs worldwide

Those have the potential to provide metabolic effects without increasing side effects of pruritus and elevated LDL

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On paper the two are complementary rather than redundant one stops a leak, the other adds water to the tank

Moreover, as natural products, they are very safe, provided that production quality is maintained, and no impurities or additional substances are present (e.g., citrinin in red rice)