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"Aging- and photoaging-dependent changes of enzymic and nonenzymic antioxidants in the epidermis and dermis of human skin in vivo"

Supports metabolic flexibility in both fasted and fed states Useful for individuals with insulin resistance or post-cycle metabolic slowdown May complement fasting, low-carb, or Clean Carbs strategies for performance athletes MOTS-c administration significantly improved glucose tolerance and insulin sensitivity in aged and high-fat-fed mice. Lu et al., Aging Cell Promotes Fat Loss Without Muscle Breakdown By activating AMPK and mitochondrial uncoupling, MOTSc encourages the body to burn fat more efficiently especially during caloric restriction or training

The likely rationale for this decision is that animal studies have found dietary glucose (the sugar in food and drinks) can suppress GH levels in rats [8], and GH levels in humans are known to peak in the late evening, just before bedtime

It's used more for systematic inflammatory issues

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