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Abbreviations GA: General anaesthesia GAs: General anaesthetics POCD: Postoperative cognitive dysfunction NMDA: N -Methyl-d-aspartate GABA: Gamma-aminobutyric acid DMT1: Divalent metal transporter 1 NTBI: Non-transferrin-bound iron DFP: Deferiprone IRP: Iron regulatory proteins TfR1: Transferrin receptors 1 Mfrn: Mitoferrin mPTP: Mitochondrial permeability transition pore MMP: Mitochondrial membrane potential References Disma N, OLeary JD, Loepke AW, Brambrink AM, Becke K, Clausen NG, De Graaff JC, Liu F, Hansen TG, McCann ME, et al

The discovery, characterization, and clinical development of glucagon-like-peptide-1 (GLP-1) spans more than 30 years and includes contributions from multiple investigators, science recognized by the 2017 Harrington Award Prize for Innovation in Medicine