The study medication was stored in a study refrigerator and protected from light until 30 min before administration, when it was allowed to come to room temperature, for participant comfort during administration
The European Food Safety Authority (EFSA) issued a 2018 scientific opinion concluding that GTE doses at or above 800 mg EGCG/day were associated with "liver safety concerns" and that doses above 400 mg EGCG/day in supplements "could not be considered safe" for regular use [6]
10.1093/humupd/dmz046 [DOI] [PubMed] [Google Scholar] Zhang T., He Q., Xiu H., Zhang Z., Liu Y., Chen Z., et al
Appl Microbiol Biotechnol 98(24):1005310064
Skin barrier and collagen support: Niacinamide and Vitamin C support the ceramide-rich skin barrier and provide co-factors for collagen hydroxylation, supporting skin firmness and reducing TEWL relevant to Singapore's humid, sun-intense equatorial climate