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While the evidence is largely based on case reports and physiological rationale rather than large controlled studies, this has led to increased awareness and the development of specific management strategies

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[ 7,8] The cholinergic system regulates executive function either by direct action, or by modulating other neurotransmitter systems (e.g., dopamine, norepinephrine, and serotonin signaling)

Written informed consent was obtained from all patients for being included in the study