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The FTO gene variant (rs9939609) affects appetite regulation and metabolic rate, while GLP1R genetic markers (rs6923761) influence receptor sensitivity and medication efficacy
They lower cortisol (your stress hormone), support insulin sensitivity, and reduce low-grade inflammation which means: Fewer crashes and cravings Less belly fat storage Better sleep and recovery For women in their 40s and 50s on the Josie program, this shift often brings more energy and better sleep too
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Wnt/beta-Catenin Pathway The Wnt/-Catenin pathway regulates cell proliferation, polarity, stem cell pluripotency and cell fate decisions during embryonic development and tissue homeostasis
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