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Oxidative stress plays a central role in neurogenic changes in DS 4,17
Similar to nonsilent immune forms of regulated necrosis, ferroptotic cell death can release damage-associated molecular patterns (DAMPs) that promote the development of multiple inflammatory diseases and trigger the innate immune system
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Vadhan-Raj S, Broxmeyer HE, Andreeff M , Bandres JC, Buescher ES, Benjamin RS, Papadopoulos NE, Burgess A, Patel S, Plager C, Hittelman WN, McAlister I, Garrison L, Williams DE
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