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note that lactulose is not recommended as it may worsen bloating [14] [18] For abdominal pain : Antispasmodics (mebeverine, peppermint oil) taken before meals For global symptoms : Tricyclic antidepressants at low doses, with selective serotonin reuptake inhibitors (SSRIs) considered if TCAs are ineffective or not tolerated Psychological therapies have robust evidence in IBS management, including cognitive behavioural therapy (CBT), gut-directed hypnotherapy, and mindfulness-based interventions

Some GLP-1 drugs are only covered for diabetes, while others are covered for weight management

Akopyan represented Novo Nordisk in the patent filing

GLP-1s for Weight Loss: How They Work & Who They Help What Are GLP-1 Receptor Agonists

T1 may promote immune tolerance and regulation, allowing the body to better encourage proper immune response rather than broadly suppressing the immune system