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(7) Yanqing Li, Chi Zhang, Haicheng Cheng, LinYan Lv, et al (2024) FOXO4-DRI improves spermatogenesis in aged mice through reducing senescence-associated secretory phenotype secretion from Leydig cells Experimental Gerontology

The invariant cis -Pro residue is located in the loop region before 3 and is thought to be implicated in the maintenance of the enzyme fold rather than playing a role in the enzymatic reaction (Figure 3A) (Allocati et al., cis -proline is hydrogen-bonded to the backbone of CysGS (cysteine residue of glutathione) (Figure 3A)

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Sulforaphane reduces apoptosis and oncosis along with protecting liver injury-induced ischemic reperfusion by activating the Nrf2/ARE pathway