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GLP-1 receptors in reward-related brain areas (e.g., nucleus accumbens, insula) and the hindbrain allow GLP-1 and its agonists to regulate appetiteeven when hypothalamic structures are damaged by tumors

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Some researchers have conceptually explored combining both strategies for potentially synergistic effects on intracellular NAD+ levels, though no published data exists for this specific combination

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Funnel plots were used in analysis with 10 studies for heterogeneity followed by sub-analysis to locate the source of heterogeneity ( Table 5 )

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