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thus, this may also be a contributing factor to the differences in observed %WL in BARI-STEP and STEP 1

Satiety Signals: It enhances satiety signals in the brain, contributing to the feeling of fullness and aiding in controlling portion sizes and reducing overall food intake

It induces insulin secretion it prevents apoptosis which means death of pancreas cells, this is where insulin is secreted from generated It stimulates glucagon secretion and fat accumulation

These mechanisms are investigated to better understand how multi-receptor agonist peptides influence intracellular signaling cascades, receptor binding dynamics, and downstream molecular responses

We acknowledge support from the Netherlands CardioVascular Research Initiative (CVON-PREDICT project, CVON 2012-10)