Similarly, PDX experiments in this study showed that tumors with high ACTL6A expression were more sensitive to administration of BSO, a GCLC inhibitor
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A Small Molecule Activator of p300/CBP Histone Acetyltransferase Promotes Survival and Neurite Growth in a Cellular Model of Parkinson's Disease
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[13] [19] Specifically, the function of GSTs in this role is twofold: to bind both the substrate at the enzyme's hydrophobic H -site and GSH at the adjacent, hydrophilic G-site, which together form the active site of the enzyme