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MTC is a rare form of thyroid cancer originating from parafollicular C-cells, accounting for approximately 3-4% of all thyroid malignancies

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For example, saxagliptin protected the mitochondrial function in PD rat models by up-regulating complex I and the anti-apoptotic protein Bcl-2 (72), while long-term use of exendin-4 in rodents promoted the function of hippocampal nerves, and improved motor function and behavior (73)