This information may then give rise on one hand to an interoceptive, anti-inflammatory feedback signal sent to the inflamed region via ANS-derived catecholamines and HPA axis-derived corticosteroids, and on the other hand, to the involvement of limbic and cortical brain regions, which modulate the interoceptive networks by involving emotion, memory and cognition
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Phosphorylated Parkin is able to ubiquitinate various proteins on OMM surface, which of them further are phosphorylated by PINK1
Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans, Stier H., Vos E., Kenley D., Journal (Journal of Endocrinology and Metabolism, Volume 3, Issues 12, 2013, Pages 715)