It is a complex condition with a multitude of etiologies, including diabetes, hypertension, glomerulonephritis, and polycystic kidney disease (Stevens et al., 2024)
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Transport of glutathione diethyl ester into human cells
In a similar model of LDLr-/- mice, alogliptin (30 mg/kg/d for 7 weeks) reduced the collagen-1 mRNA expression and triglyceride levels in hepatic cells