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Salva S, Marranzino G, Villena J, Aguero G, Alvarez S

Both intrinsic and extrinsic pathways require the activation of the proteolytic caspase cascade, ultimately dismantling and eliminating the dying cell [122]

(ONOO) is a damaging oxidant which can cause lipid peroxidation, protein oxidation, protein nitration and enzyme inactivation

We processed each tilted data set individually using cryoSPARC 40 and focused on enriching for rare particle orientations by iteratively training Topaz 39 to pick non-preferred orientation particles for each tilt set

Conditions like pernicious anemia, for instance, require ongoing B12 injections for life due to a fundamental absorption issue