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3 The role of ferroptosis in osteoarthritis Osteoarthritis (OA) is characterized by pathological changes affecting the entire joint structure, with degenerative alterations in articular cartilage being the primary manifestation (Findlay and Atkins, 2014)

It is studied in experimental models for effects on body composition, lipolysis, and IGF-1 modulation without significant cortisol or prolactin elevation.

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