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There is no reliable way to determine whether heat-exposed Ozempic remains effective simply by visual inspection, as the solution may still appear clear and colourless despite molecular degradation

1 The FLOW trial achieved its primary endpoint with Ozempic 1 mg, demonstrating a statistically significant and superior 24% relative risk reduction of kidney disease worsening, kidney failure (end-stage kidney disease), and death due to cardiovascular disease (4.9% absolute risk reduction at 3 years) compared to placebo, when added to standard of care

But the totality of information from the danuglipron trials, the case of possible liver damage and recent input from regulators have led it to discontinue development, the company said