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2010 Jul;44(6):402-6

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These are not secondary curiosities for patients with obesity who also live with hypertension, dyslipidaemia, or elevated inflammatory markers, systemic risk reduction may be as clinically important as the weight loss itself

Hygum K, Harslf T, Jrgensen NR, Rungby J, Pedersen SB, Langdahl BL (2020) Bone resorption is unchanged by liraglutide in type 2 diabetes patients: a randomised controlled trial

Once one prolongs into a rehabilitation program and the MCL may feel somewhat stiff prior to getting on a stationary bike, warming it up with a hot pad may be indicated in those circumstances