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In this trial, 3,183 adult patients with inadequately controlled type 2 diabetes mellitus and atherosclerotic CV disease were randomized to semaglutide tablets 14 mg orally once daily or placebo for a median observation time of 16 months

The FDA has approved semaglutide to treat cases of obesity with underlying atherosclerotic cardiovascular disease or a history of heart attack

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Phentermine's stimulant properties can cause insomnia, restlessness, anxiety, and mood changes

According to the manufacturer of semaglutide, the concentration of the drug in the bloodstream typically reaches a steady level after 45 weeks of once-weekly use