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BPC-157 significantly accelerated tendon fibroblast outgrowth, increased cell survival under oxidative stress, and enhanced cell migration in a dose-dependent manner, effects attributed to activation of the FAK-paxillin pathway central to tendon repair

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Journal reference: Tatum KL, Dahman B, Stevenson A, et al

283 Notably, 1026 sites of lactylated proteins were identified in myocardial tissues from I/R rats by lactylation modification omics and were prominently enriched in the TCA cycle pathway

15-LOX-1 inhibits p21 (Cip/WAF 1) expression by enhancing MEK-ERK 1/2 signaling in colon carcinoma cells