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How to Safely Manage GLP-1 Discontinuation If you decide to stop GLP-1 therapy with your provider's guidance, gradual tapering rather than abrupt cessation may ease the transition

It is a GLP-1 receptor agonist, a type of drug that mimics the action of a naturally occurring hormone called glucagon-like peptide-1 (GLP-1) a natural hormone your body produces after eating

doi: 10.1016/j.crmicr.2025.100347 133 NozueMShimazuTSasazukiSCharvatHMoriNMutohMet al

The nasal passage provides a direct pathway via the mucosa into the blood circulation, thereby avoiding enzymatic degradation in the gut

This gradual approach allows gastrointestinal adaptation and improves tolerability